The TP508 Solution for Tissue Repair

a.    Thrombin peptide Chrysalin stimulates healing of diabetic foot ulcers in a placebo-controlled phase I/II study. Fife C, Mader JT, Stone J, Brill L, Satterfield K, Norfleet A, Zwernemann A, Ryaby JT, Carney DH. Wound Repair Regen. 2007 Jan-Feb;15(1):23-34. doi: 10.1111/j.1524-475X.2006.00181.x.PMID: 17244316       https://pubmed.ncbi.nlm.nih.gov/17244316/

b.    Could rusalatide acetate be the future drug of choice for diabetic foot ulcers and fracture repair?  Carney DH, Olszewska-Pazdrak B.Expert Opin Pharmacother. 2008 Oct;9(15):2717-26. doi: 10.1517/14656566.9.15.2717.PMID: 18803458 Review.  https://pubmed.ncbi.nlm.nih.gov/18803458/

c.    Thrombin peptide TP508 stimulates cellular events leading to angiogenesis, revascularization, and repair of dermal and musculoskeletal tissues.  Ryaby JT, Sheller MR, Levine BP, Bramlet DG, Ladd AL, Carney DH. J Bone Joint Surg Am. 2006 Nov;88 Suppl 3:132-9. doi: 10.2106/JBJS.F.00892.PMID: 17079379 Review.  https://pubmed.ncbi.nlm.nih.gov/17079379/